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标题 老年肝癌切除术患者全麻术后苏醒延迟的高危因素分析
范文

    赵建立 韦国温 黄敏坚 黄红梅

    

    

    【摘要】 目的:探討老年肝癌切除术患者全麻术后苏醒延迟的高危因素。方法:回顾性分析2015年4月-2019年3月于笔者所在医院接受肝癌切除术的老年肝癌患者临床资料,患者均行全身麻醉,根据患者苏醒情况,选取13例发生苏醒延迟的患者作为观察组(麻醉苏醒时间≥2 h),另选取107例未发生苏醒延迟的患者作为对照组(麻醉苏醒时间<2 h),经Logistic回归分析苏醒延迟的高危因素。结果:两组性别占比比较,差异无统计学意义(P>0.05);观察组年龄≥70岁、身体质量指数(BMI)≥25 kg/m2、美国麻醉医师协会(ASA)分级≥Ⅲ级、合并高血压、合并冠心病、术中体温过低、术中输液量≥3 000 ml、麻醉史、手术时间≥4 h占比高于对照组,差异均有统计学意义(P<0.05);经Logistic回归分析显示,年龄(≥70岁)、BMI(≥25 kg/m2)、ASA分级(≥Ⅲ级)、合并高血压、合并冠心病、术中体温过低、术中输液量(≥3 000 ml)、麻醉史、手术时间(≥4 h)为老年肝癌切除术患者全麻术后苏醒延迟的相关影响因素(OR>1,P<0.05)。结论:年龄≥70岁、BMI≥25 kg/m2、ASA分级≥Ⅲ级、合并高血压及冠心病、术中体温过低、术中输液量≥3 000 ml、麻醉史、手术时间≥4 h均为老年肝癌切除术患者全麻术后苏醒延迟的高危因素,可为临床制定预防性措施提供参考。

    【关键词】 肝癌切除术 老年 全身麻醉 苏醒延迟

    doi:10.14033/j.cnki.cfmr.2020.22.024 文献标识码 B 文章编号 1674-6805(2020)22-00-03

    [Abstract] Objective: To investigate the high risk factors of delayed recovery after general anesthesia in senile patients with hepatectomy for liver cancer. Method: The clinical data of senile liver cancer patients with hepatectomy in the hospital from April 2015 to March 2019 were retrospectively analyzed. All patients underwent general anesthesia. According to the recovery of patients, 13 patients with delayed recovery were selected as observation group (anesthesia recovery time ≥2 h), and 107 patients without delayed recovery were selected as control group (anesthesia recovery time <2 h). The high risk factors for delayed recovery were analyzed by Logistic regression. Result: There was no statistical difference in the proportion of gender between two groups (P>0.05). The proportion of age ≥70 years old, body mass index (BMI) ≥25 kg/m2, America Society of Anesthesiologist (ASA) grading ≥grade Ⅲ, combined with hypertension, combined with coronary heart disease, intraoperative hypothermia, intraoperative infusion volume ≥3 000 ml, history of anesthesia, operation time ≥4 h in observation group were significant higher than those in the control group (P<0.05). Logistic regression analysis showed that age (≥70 years old), BMI (≥25 kg/m2), ASA grading (≥grade Ⅲ), combined with hypertension, combined with coronary heart disease, intraoperative hypothermia, intraoperative infusion volume (≥3 000 ml), history of anesthesia, operation time (≥4 h) were related influencing factors for delayed recovery after general anesthesia in senile patients with hepatectomy for liver cancer (OR>1, P<0.05). Conclusion: Age ≥70 years old, BMI ≥25 kg/m2, ASA grading ≥grade Ⅲ, combined with hypertension coronary and heart disease, intraoperative hypothermia, intraoperative infusion volume ≥3 000 ml, history of anesthesia, operation time ≥4 h are the high risk factors for delayed recovery after general anesthesia in senile patients with hepatectomy for liver cancer, which can provide reference for clinical development of preventive measures.

    综上所述,老年肝癌切除术患者全麻术后苏醒延迟的高危因素包括年龄(≥70岁)、BMI(≥25 kg/m2)、ASA分级(≥Ⅲ级)、合并高血压、合并冠心病、术中体温过低、术中输液量(≥3 000 ml)、麻醉史、手术时间(≥4 h),临床需在术前加强基础疾病干预及术中体征监测,注意术中保温,同时控制输液量及麻醉剂量,从而避免苏醒延迟情况发生。

    参考文献

    [1]邹亚媛,唐艳花.经腹肝癌切除术术中低体温危险因素logistic回归分析与防护措施[J].护理实践与研究,2018,15(21):117-119.

    [2]张帮健,魏寿存,杨小燕.右美托咪啶联合丙泊酚麻醉对肝癌切除术患者围手术期血清细胞因子和术后苏醒质量的影响[J].实用肝脏病杂志,2019,22(2):264-267.

    [3]李想.全身麻醉下肝肿瘤切除术患者术后苏醒延迟的相关危险因素分析[D].南宁:广西医科大学,2017.

    [4]沈晓瑜,周利,徐国勇,等.全身麻醉下肺癌根治术患者麻醉苏醒延迟的高危因素分析[J].广东医学,2019,40(21):3021-3024.

    [5]张涛,郭庆林.不同浓度七氟醚联合丙泊酚麻醉对腹腔镜肝癌切除术患者术后苏醒及安全性的影响[J].实用癌症杂志,2017,32(11):1855-1859.

    [6]李明良,姚素英,黄仕英,等.术毕呋塞米静注对静脉全身麻醉老年患者术后苏醒质量的改善作用[J].山东医药,2019,59(15):58-60.

    [7]付武昌,冯艳,左友波,等.右美托咪定辅助全身麻醉下肺部分切除術患者术后苏醒延迟及寒颤的影响研究[J].成都医学院学报,2018,13(2):205-209.

    [8]张伟,冷会,陈淼,等.米库氯铵致血清胆碱酯酶缺乏患者全麻苏醒延迟1例并文献回顾[J].重庆医学,2019,48(5):896-898.

    [9]邵兵,李宇,光洪德.麻醉后监测治疗室全麻患者苏醒延迟的原因与护理对策[J].护士进修杂志,2017,32(13):1222-1224.

    [10]郭静,杨改生.Narcotrend指导全身麻醉对患者麻醉苏醒时间影响的Meta分析[J].中国医药导报,2017,14(1):61-67.

    [11]曹桂林,张建欣,张传阳,等.监测麻醉深度对老年患者术中麻醉药用量及术后恢复的影响[J].国际麻醉学与复苏杂志,2017,38(3):221-272.

    [12]沈雷兵,周新华,沈伯雄.术中保温对老年病人全麻苏醒时间及苏醒期丙泊酚效应室浓度的影响[J].安徽医药,2017,21(6):1045-1048.

    (收稿日期:2020-01-14) (本文编辑:郎序莹)

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