派力奥局部应用治疗下颌智齿冠周炎疗效观察

    高秦　马东洋

    

    [摘要]目的：观察派力奥软膏在智齿冠周炎治疗中的疗效。方法：选取2018年3月-2019年11月笔者科室诊治的92例急性下颌智齿冠周炎患者为研究对象，随机分为派力奥实验组和碘甘油对照组，实验组盲袋内将派力奥软膏缓慢注入袋底，1次给药;对照组盲袋内用探针导入2%碘甘油，1次/d，连续治疗3d，两组患者用药5d后观察疗效及安全性。结果：治疗后，对照组和治疗组的总有效率分别为96%、78%，治疗组疗效明显优于对照组。结论：派力奥软膏是治疗下颌智齿冠周炎的一种安全、有效的药物，值得临床推广应用。

    [关键词]派力奥;米诺环素;智齿冠周炎;局部用药;疗效

    [中图分类号] R781.4+2? ? [文献标志码]A? ? [文章编号]1008-6455（2020）08-0155-02

    The Effect of Minocycline Hydrochloride Ointment on Pericoronitis

    of? Wisdom Tooth

    GAO? Qin1，MA Dong-yang2

    （1.Department of Ophthalmology and Otorhinolaryngology，People's Liberation Army 96604 Troop Hospital，Lanzhou 730030，Gansu，China; 2. Department of Maxillofacial Surgery， PLA Joint Logistic Support Force 940 Hospital， Lanzhou 730000， Gansu，China）

    Abstract： Objective To observe the effect of Minocycline Hydrochloride Ointment on pericoronitis of wisdom tooth. Methods Select our hospital from March 2018 to November 2019 were among the 92 cases of pericoronitis of? wisdom tooth as research object， 92 patients with pericoronitis were divided into 2 groups. One group was treated with Minocycline Hydrochloride Ointment and the other group was treated with iodoglycerin . Patients in the treatment group were treated with Minocycline Hydrochloride Ointment one time. Patients in the control group were treated with iodoglycerin one time daily. continuous treatment three days， 5days later. The effect of two groups was observed. Results? The clinical effect of two groups were 96% and 78%， The cilinical effect of the group treated with Minocycline Hydrochloride Ointment was much better than the group treated with iodoglycerin. Conclusion The treatment of pericoronitis of wisdom tooth with Minocycline Hydrochloride Ointment is effective， safe and worthy of promotion.

    Key words：palio;minocycline hydrochloride ointment; pericoronitis;topical remedy;tjerapy

    智齿冠周炎是口腔科的常见病和多发病，是发生在第三磨牙周围软组织的炎症，由于下颌第三磨牙萌出最晚，萌出位置常发生不足，智齒萌出时牙齿萌出不全或异位阻生，致使部分牙冠被牙龈覆盖，形成盲袋，容易积存食物残渣及细菌，因其位置较深，而日常口腔清洁较难将其彻底清理干净，最终可促使细菌不断繁殖生长[1]，导致智齿冠周发生炎症，临床上以下颌智齿冠周炎多见[2]，通常发生在18～25岁的青年人群。早期一般全身无明显反应，仅表现患侧后牙区胀痛不适，进食和吞咽时疼痛加重，进一步发展局部呈自发性跳痛，当炎症侵犯到咀嚼肌时会出现张口受限，局部炎症继续发展，出现全身症状及邻近组织间隙感染等并发症[3]。因此，早期有效控制感染是治疗关键。为进一步探讨局部使用派力奥治疗智齿冠周炎的临床可行性，笔者科室应用派力奥软膏作为局部用药，获得了较好的临床疗效，现将结果报道如下。

    1? 资料和方法

    1.1 一般资料：选取笔者医院口腔门诊2018年3月-2019年11月诊治的急性下颌智齿冠周炎早期患者92例，其中男70例，女22例，年龄18～25岁，多表现为患侧智齿萌出不全（其中正中阻生9例、近中阻生54例、远中阻生29例），冠周软组织红肿疼痛，牙龈红肿糜烂，有深盲袋，袋内溢脓，张口受限等局部症状，均无明显间隙感染及全身症状，均未口服抗菌素。将患者随机分为派力奥组46例和对照组46例。